DR. SZE, Stephen Cho Wing (施祖榮)

Assistant Professor (Research)

Assistant Director (Admin), the Golden Meditech Centre for NeuroRegeneration Sciences

EDUCATION

PhD, CUHK
BSc, China Pharmaceutical University
BSc, HKBU

 

 

 

CURRENT RESEARCH INTERESTS

  • Aging research – ovarian inflammaging (inflammation and aging).
  • Cancer Research – Cancer prevention and treatment via anti-inflammation using nature product/Chinese medicine

HIGHLIGHT PROJECTS / AWARDS AND ACHIEVEMENTS

  • Aging research – ovarian inflammaging (inflammation and aging). (GRF: Ref: 12102919; 2019-2021); aging and neurological disease.
  • Cancer Research – Cancer prevention and treatment via anti-inflammation using nature product/Chinese medicine. (HMRF: Ref: 14151791; 2017-2019

EDITORIAL BOARD / PANEL

  • Editor, Annals of Medicinal Chemistry and Research (USA). (2016-present)
  • Asso Editor, Special issue, Frontier in Pharmacology. (2018)
  • Review Editor, Frontier in Pharmacology. (2016-present)
  • Member of Editorial board, Integrative Cancer Therapy. (2016-present)
  • 世界中醫藥學會聯合會(世中聯)-癌症姑息治療研究專業委員會中常務理事(2016-present)
  • 世界中醫藥學會聯合會(世中聯)-中國民族醫藥學會腫瘤醫學分會常務理事(2015-present)

SELECTED PUBLICATIONS

  1. Zhang SQ, Lin KL, Law CY, Liu B, Fu XQ, Tse WS, Wong SSM, Sze SCW*,Yung KKL*. (2019) Oleanolic acid enhances neural stem cell migration, proliferation, and differentiation in vitro by inhibiting GSK3β activity. Cell Death Discovery. 2019 Jul 10;5:116.
  2. Lin K, Liu B, Lim SL, Fu XQ, Sze SCW, Yung KKL*, Zhang SQ*. (2019) 20(S)-protopanaxadiol promotes the migration, proliferation, and differentiation of neural stem cells by targeting GSK-3β in the Wnt/GSK-3β/β-catenin pathway. Journal of Ginseng Research (available online 25 Mar 2019). https://doi.org/10.1016/j.jgr.2019.03.001
  3. Zhang L, Ng TB, Lam JKW, Wang SW, Lao L, Zhang KY, Sze SCW*. (2019) Research and development of proteins and peptides with therapeutic potential from yam tubers. Current Protein & Peptide Science. Curr Protein Pept Sci. 2019;20(3):277-284.
  4. Wang X, Wang GC, Rong J, Wang SW, Ng TB, Zhang YB, Lee KF, Zheng L, Wong HK, Yung KKL*, Sze SCW*. (2018) Identification of Steroidogenic Components Derived from Gardenia jasminoidesEllis Potentially Useful for Treating Postmenopausal Syndrome. Frontiers in Pharmacology. 2018 May 30;9:390. doi: 10.3389/fphar.2018.00390.
  5. Liu JY, Chen XX, Chen HY, Shi J, Leung GP, Tang SC, Lao LX, Yip HK, Lee KF, Sze SCW, Zhang ZJ, Zhang KY. (2018) Downregulation of Aquaporin 9 Exacerbates Beta-amyloid-induced Neurotoxicity in Alzheimer’s Disease Models In vitroand In vivo. Neuroscience, 394, 72-82.
  6. Chen XX, Leung GPH, Zhang ZJ, Xiao JB, Lao LX, Feng F, Mak JCW, Wang Y, Sze SCW*, Zhang YB*. (2017) Proanthocyanidins from Uncaria rhynchophyllainduced apoptosis in MDAMB-231 breast cancer cells while enhancing cytotoxic effects of 5-fluorouracil. Food and Chemical Toxicology, 107(Pt A): 248-260.
  7. Wang SW, Cheung HP, Tong Y, Jia L, Ng TB, Zhang YB, Zhang ZJ, Lee KF, Lam JKW, Sze SCW*.(2017) Steroidogenic Effect of Erxian Decoction for menopause via Akt/PKB pathway in vitro and in vivo. Journal of Ethnopharmacology, 195:188-195.
  8. Cheung TS, Song TH, Ng TB, Wu FH, Lao LX, Tang SC, Ho JC, Zhang KY*, Sze SCW*. (2015) Therapeutic Effects of Herbal Chemicals in Traditional Chinese Medicine on Alzheimer’s disease.
  9. Wong KL, Lai YM, Li KW, Lee KF, Ng TB, Cheung HP, Zhang YB, Lao LX, Wong RNS, Shaw PC, Wong JH, Zhang ZJ, Lam JKW, Ye WC, Sze SCW*. (2015) A Novel, Stable, EstradiolStimulating, Osteogenic Yam Protein with Potential for the Treatment of Menopausal Syndrome. Scientific Report, 5:10179.
  10. Wong KL, Wong RN, Zhang L, Liu WK, Ng TB, Shaw PC, Kwok PC, Lai YM, Zhang ZJ, Zhang YB, Tong Y, Cheung HP, Lu J, Sze SCW*. (2014) Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential. Chinese Medicine, 9:19.

Selected Patent:

  • Sze SCW, Wong KL, Tong Y, Zhang YB, Cheung HP. Novel Bioactive Protein Isolated from Chinese Yam and uses thereof. US Patent and Trademark Office, U.S. Patent No.: US9273105B2. Patent Date: Mar. 1, 2016. (Patent has been licensed on Dec, 2016 for functional food and drug development)

Chapters in textbook:

  1. English Book Chapter for “Chinese Medicine Research”《中醫科研英語教程》人民衛生出版社:
  2. Chief Editor – Prof Y TONG, previous Director, School of Chinese Medicine, HKU
    • Chapter 5: Menopausal Research in Chinese Medicine. Sze SCW, Ng TB, Tong Y. 2016
    • Chapter 8: Preparation of Manuscript and Procedures for Publication. Sze SCW, Ng TB. 2016

 

CONTACT DETAILS

Email: scwsze@hkbu.edu.hk
Office: RRS 908
Office Tel: (+852) 3411 2318

Website: http://gcns.hkbu.edu.hk/staff/5eae8b1c710eca7798929cc4