DR. YUE, Patrick Ying Kit (余英傑)

Fellow, Higher Education Academy, UK
Lecturer I
Programme Director for BSc (Hons) in Applied Biology
Member, Undergraduate Studies Committee
EDUCATION
Ph.D. HKBU
B.Sc. (Hons.) HKBU
AWARDS AND RECOGNITIONS

  • Long Service Award (20-years). 2020 HKBU
  • First class award. 2014 Ministry of Education Higher Education Outstanding Scientific Research Output Awards (Science and Technology) State Natural Science.
  • Long Service Award (15-years). 2015 HKBU.
  • Certificate of Appreciation. 2015 Faculty of Science/ HKBU.
  • Long Service Award (10-years). 2010 HKBU.

PATENTS

  • United State Patent (US 9,533,301 B2) 2017. Title of invention: Mechanical cell wounder device and related method.
  • China Patent (CN200710127846) 2007. Title of invention: Mechanical cell wounder device and related method.

COMPANY HOLDER

  • R&P Technology Limited. .

SERVICE

  • HKDSE. Hong Kong Examinations and Assessment Authority
  • Curriculum Development Council, Hong Kong Examinations and Assessment Authority
  • Local TV program – 學是學非, 歎得好健康, 都市閒情,東張西望, 長命不老, 最强生命線, ,恐怖真相, 鏗鏘集2014 – Date.

INTERNATIONAL/LOCAL COMPETITION ADJUDICATOR

  • The Hong Kong Youth Science and Technology Innovation Competition (2018 – data)
  • BIOMOD Jamboree. International Bio-Molecular Design Competition. Wyss Institute for Biologically Inspired Engineering, Harvard University. 2012 – Date.
  • The 20th Hong Kong Youth Science and Technology Innovation Competition
  • The 69th Intel International Science and Engineering Fair (Intel ISEF) – Hong Kong Regional Final
  • 51st Joint School Science Exhibition – Proposal Competition

STEM, GIFTED EDUCATION and COMMUNITY OUTREACH

  •  Theme-based school talks (Service users: Local Schools)
  •  Theme-based summer workshops (Service users: Local Schools)
  •  STEM & Gifted education (Service user: Local Schools Local Schools and The Hong Kong Academy   for Gifted Education

FUNDED TEACHING PROJECTS

  • Developing Online Courses/Blended Learning Initiatives with FutureLearn. 2017-2018
  • Course Enhancement Funds. UGC T&L Project on Information Literacy: Enhancing information literacy (IL) in Hong Kong higher education. 2nd semester, 2016-2017
  • Course Enhancement Funds. UGC T&L Project on Information Literacy: Enhancing information literacy (IL) in Hong Kong higher education. 1st semester 2016-2017
  • Teaching Development Grant. Project title: Molecular biology/ Introduction to biotechnology – Multimedia education packages for studying genetic modified (GM) organisms (GM-foods). 2010

CURRENT RESEARCH INTERESTS

  •  Pharmacological and biomedical effects of Chinese medicines and natural products
  •  Research and development of high throughput screening platform for cell motility study
  •  Biological impacts and toxicological study of environmental pollutants and emerging contaminants

RESEARCH PROJECTS

  1. Tumoricidal effects of Panax Ginseng on nasopharyngeal carcinoma. (Co-I: Prof. Ricky NS Wong). Source: FRG/ HKBU.
  2. The anti-angiogenic activities of indirubin derivatives (indirubin-3’-oxime and E804)(Co-I: Dr. Kelvin SY Leung/ Shi Jue). Source: FRG/ HKBU.
  3. Molecular Biology / Introduction to Biotechnology – Multimedia Education Packages for Studying Genetic Modified Organisms. (Co-I: Prof. JH Zhang/ Ricky NS Wong/ NK Mak/ Chris KC Wong/ YL Xia). Source: TDG/ HKBU.

SELECTED PUBLICATIONS

Book

  1. PYK Yue* and RNS Wong. The Ginsenosides: Yin and Yang in Angiogenesis. LAP LAMBERT Academic Publishing AG & Co. KG. 2009.

Book Chapters

  1. PYK Yue*, Y Huang, RNS Wong. Ginsenoside Rg3 and Rh2: the anti-cancer and anti-angiogenic saponins from ginseng. “Anti-Angiogenesis-Drug Discovery and Development”. volume1, issue 1, p34-57. Bentham Science Publishers. 2010.
  2. PYK Yue*, YK Cheng, NK Mak, KW Leung, AST Leung, TP Fan, RNS Wong. Chapter 21 Ginseng and angiogenesis. Angiogenesis: Basic Science and Clinical Application. p.351-66. Transworld Research Network. 2007

Reviews

  1. Yue PY, Wong YY, Chan TY, Law CK, Tsoi YK, Leung KS. Review of Biological and Pharmacological Activities of the Endemic Taiwanese Bitter Medicinal Mushroom, Antrodia camphorata (M. Zang et C. H. Su) Sh. H. Wu et al. (Higher Basidiomycetes). Int J Med Mushrooms. 2012;14(3):241-56.
  2. Yue PY, Mak NK, Cheng YK, Leung KW, Ng TB, Fan DT, Yeung HW, Wong RN. Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides. Chin Med. 2007; 15;2:6. Review. (Top accessed journal)
  3. Fan TP, Yeh JC, Leung KW, Yue PY, Wong RN. Angiogenesis: from plants to blood vessels. Trends Pharmacol Sci. 2006; 27(6):297-309. Review.

Research Articles (*-corresponding author #-equal contribution)

  1. Tang MKS, Yue PY, Ip PP, Huang RL, Lai HC, Cheung ANY, Tse KY, Ngan HYS, Wong AST. Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface. Nat Commun. 2018;9(1):2270. (Impact Factor – 11.05)
  2. Yue PY, Ha WY, Lau CC, Cheung FM, Lee AW, Ng WT, Ngan RK, Yau CC, Kwong DL, Lung HL, Mak NK, Lung ML, Wong RN. MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma. Sci Rep. 2017;7(1):12012.
  3. Keung MH, Chan LS, Kwok HH, Wong RN, Yue PY*. Role of microRNA-520h in 20(R)-ginsenoside-Rg3-mediated angiosuppression. J Ginseng Res. 2016;40(2):151-9.
  4. Chan YK, Zhang HM, Liu P, Tsao GS, Lung ML, Mak NK, Wong RN, Yue PY*. Proteomic analysis of Exosomes from Nasopharyngeal Carcinoma Cell identifies Intercellular Transfer of Angiogenic Proteins. Int J Cancer. 2015;137(8):1830-41.
  5. Law KM, Kwok HH, Poon PY, Lau CC, Jiang ZH, Tai WC, Hsiao WW, Mak NK, Yue YK*, Wong RN*. Ginsenoside compound K induces apoptosis in nasopharyngeal carcinoma cells via activation of apoptosis-inducing factor. BMC Chin Med. 2014; 9:11.
  6. Chan LS#, Yue PY#, Wong YY, Wong RN. MicroRNA-15b contributes to ginsenoside-Rg1-induced angiogenesis through increased expression of VEGFR-2. Biochem Pharmacol. 2013; 86(3):392-400.
  7. Chan YK, Kwok HH, Chan LS, Leung KS, Shi J, Mak NK, Wong RN, Yue PY*. An indirubin derivative, E804, exhibits potent angiosuppressive activity. Chan YK, Biochem Pharmacol. 2012; 83(5):598-607.
  8. Chan LY, Kwok HH, Chan RW, Peiris MJ, Mak NK, Wong RN, Chan MC, Yue PY*. Dual functions of ginsenosides in protecting human endothelial cells against influenza H9N2-induced inflammation and apoptosis. J Ethnopharmacol. 2011; 137(3):1542-6.
  9. Chan LS#, Yue PY#, Kok TW, Keung MH, Mak NK, Wong RN. Ginsenoside-Rb1 Promotes Adipogenesis Through Regulation of PPARγ and MicroRNA-27b. Horm Metab Res. 2012;44(11):819-24.
  10. Chan LY, Kwok HH, Chan RW, Peiris MJ, Mak NK, Wong RN, Chan MC, Yue PY*. Dual functions of ginsenosides in protecting human endothelial cells against influenza H9N2-induced inflammation and apoptosis. J Ethnopharmacol. 2011; 137(3):1542-6.
  11. Yue PY, Leung EP, Mak NK, Wong RN. A simplified method for quantifying cell migration/wound healing in 96-well plates. J Biomol Screen. 2010; 15(4):427-33.
  12. Kwok HH, Ng WY, Yang MS, Mak NK, Wong RN, Yue PY*. The ginsenoside protopanaxatriol protects endothelial cells from hydrogen peroxide-induced cell injury and cell death by modulating intracellular redox status. Free Radic Biol Med. 2010; 48(3):437-45.
  13. P Yue, DYL Wong, P.K. Wu, PY Leung, NK Mak, HW Yeung, L. Liu, ZW Cai, ZH Jiang, TPD Fan, Ricky N.S. Wong. The angiosuppressive effects of ginsenoside-Rg3. Biochem Pharmacol. 2006; 72(4):437-45.
  14. Yue PY, Wong DY, Ha WY, Fung MC, Mak NK, Yeung HW, Leung HW, Chan K, Liu L, Fan TP, Wong RN. Elucidation of mechanisms underlying the angiogenic effects of ginsenoside Rg1 in vivo and in vitro. Angiogenesis. 2005; 8(3):205-16.

CONTACT DETAILS

Email: patrick@hkbu.edu.hk
Office: RRS 836
Office Tel: (+852) 3411 5832
Facebook Fans Page (Dr. Yue 余博士)